Youssef Ezeddin Eassa wrote around 200 short stories, 9 novels 6 plays and a good number of poems, besides almost 400 pieces of radio drama. Unlike most Egyptian or Arab writers, his writings do not cover a local area or a specific place, but he speaks about humanity everywhere, with a global prospective. He was a man from the east, who looked upon the west with a friendly eye, believing earth to be one place where mankind live, feel, suffer and share one destiny.
Known as a 'Master of Symbolic Fiction' , in his writings he has a world of his own where a fertility of imagination is molded with symbol to depict our real world. This original mold is spontaneous and together with the simplicity of his style, they captivate a reader to the very last word. Mostly, he is a philosophical sarcastic writer, mystic and at times bitter. His works were inspired by his intellect and his visions of life as a thinker, scientist, poet and artist, reflecting an insight in life, thought and society. He was a man of his century; arts, paintings, sciences, music, philosophies of the age and concepts of modernism all appeared in his literature giving it a most distinguished and original characteristic.
Alongside with fiction, he wrote over a hundred articles and weekly columns in the most prominent papers and magazines in Egypt and the Middle East . Moreover, he wrote analytical essays introducing world writers of fiction to the Arab world. He was also Head of the Club of Fiction, a member of the High Committee of Arts and Literature in Egypt , Editor of Amwag Magazine, Cultural Editor of Al Ayam Paper
In 1987, he was awarded the National Prize for Literary Art, which is the highest award in Egypt , "for founding a new school of writing style, which had influenced many writers". His award broke the rule in Egypt , for he was the first and only Egyptian writer, residing outside the capital, to obtain the National Literary Award. Cairo Writers never wished for a writer residing outside the capital to earn this prestige; yet with Eassa rules were broken. Moreover, it was extremely unusual in Egypt for a professor of science to be either nominated or to obtain a State Literary Award. Earlier in 1978, Eassa was also granted, a State Prize for his radio dramas, " For transforming the radio drama to an elite form of literature." No other Egyptian writer was granted the State Award for radio drama.